高血壓病合并糖調(diào)節(jié)受損患者血壓變異性的相關(guān)研究

　　摘要：目的  探討高血壓病合并糖調(diào)節(jié)受損（IGR）患者血糖水平與血壓變異性的關(guān)系。方法  選取2016年5月～2017年5月在承德醫(yī)學(xué)院附屬醫(yī)院全科醫(yī)療科住院的高血壓病患者，依據(jù)口服葡萄糖耐量試驗（OGTT），分為IFG組（A組）41例，IGT組（B組）42例，IFG+IGT組（C組）40例，并以46例糖耐量正常（NGT）的高血壓患者作為對照組（D組）。所有患者均進行24 h動態(tài)血壓監(jiān)測，觀察各組患者24hSBP、24hDBP、24hAPP、24hmSBPCV、24hmDBPCV等血壓變異性指標的特點。結(jié)果  各組間性別、年齡、體重、高血壓病程、家族史，以及FPG、2hPBG、HbAlc、TG比較，差異無統(tǒng)計學(xué)意義（P>0.05）。A、B、C三組24hSBP、24hDBP、24hAPP與D組相比，差異無統(tǒng)計學(xué)意義（P>0.05）;A、B、C三組24hmSBPCV、24hmDBPCV均高于D組，差異有統(tǒng)計學(xué)意義（P<0.05），以24hmSBPCV最為顯著（P<0.01），但IFG組、IGT組兩組間比較，差異無統(tǒng)計學(xué)意義（P>0.05）。結(jié)論  高血壓病合并IGR是導(dǎo)致血壓變異性增加的重要因素，對高血壓患者靶器官損害產(chǎn)生重要作用。
　　關(guān)鍵詞：糖調(diào)節(jié)受損;原發(fā)性高血壓;血壓變異性
　　中圖分類號：R544.1                              文獻標識碼：A                                    DOI：10.3969/j.issn.1006-1959.2018.05.004
　　文章編號：1006-1959（2018）05-0011-03
　　Study on Blood Pressure Variability in Patients with Hypertension Complicated with Impaired Glucose Regulation
　　DUAN Shu-ting1，WANG Yi-wei2，WANG Zhao-peng2
　�。�1.Chengde Medical College，Chengde 067000，Hebei，China;
　　2.Hospital Affiliated to Chengde Medical College，Chengde 067000，Hebei，China）
　　Abstract：Objective  To investigate the relationship between blood glucose level and blood pressure variability in patients with hypertension complicated with impaired glucose regulation.Methods  From May 2016-May 2017 hypertension patients in affiliated hospital of Chengde Medical College，according to oral glucose tolerance test （OGTT），divided into IFG group（A group）41 cases，IGT group（B group）42 cases，IFG+IGT group（C group）40 cases，46 hypertensive patients with normal glucose tolerance（NGT）were used as control group（group D）.24 h ambulatory blood pressure monitoring was performed in all patients，and the characteristics of blood pressure variability indexes such as 24hSBP，24hDBP，24hAPP，24hmSBPCV and 24hmDBPCV were observed in all the patients. Results  There was no significant difference in sex，age，body weight，course of hypertension，family history and FPG，2hPBG，HbAlc，TG between the two groups（P>0.05）.Compared with D group，there was no significant difference in 24 h SBP，24 h DBP and 24 h APP between the A，B C three groups（P>0.05）.As for 24hmSBPCV，24hmDBPCV，A，B，C three groups were higher than the D group，the difference was statistically significant（P<0.05），and 24hmSBPCV was the most significant（P<0.01）.But there was no significant difference between the IFG group and IGT groups（P>0.05）.Conclusion  Hypertension combined with IGR is an important factor to increase blood pressure variability and plays an important role in target organ damage in patients with hypertension.

相關(guān)熱詞搜索：變異性 高血壓 受損 合并 血壓